Tuesday, 14 October 2008

Software can hold drivers' cell-phone calls

When David Teater's 12-year-old son, Joe, was killed in 2004 by a driver who was talking on a cell phone, he tried to cut back on his own habit of driving and talking. It turned out to be very difficult.
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New software can detect whether a cell phone is moving at car speeds and hold calls until the drive is over.

"You have to remember to turn the phone off ... which you never remember to do. Or you have to ignore a ringing phone, which is incredibly hard," Teater said. "We've been conditioned our entire lives to answer ringing phones."

Teater became an advocate for curbing what he calls "driving while distracted," and now, he's part of a company with a technology that can help.

Aegis Mobility, a Canadian software company, announced Monday that it has developed software called DriveAssistT that will detect whether a cell phone is moving at car speeds. When that happens, the software will alert the cellular network, telling it to hold calls and text messages until the drive is over.

The software doesn't completely block incoming calls. Callers will hear a message saying the person they're calling appears to be driving. They can hit a button to leave an emergency voice mail, which is put through immediately.

Several states, including New York and California, have introduced laws against talking on a cell phone while driving, but they still allow the use of hands-free devices like Bluetooth headsets. However, studies have shown that hands-free devices may not help. It appears that it is the distraction of dialing or talking that is dangerous, rather than the act of taking a hand off the wheel.

A study by the National Highway Traffic Safety Administration in 2006 found that dialing or talking on the phone was the cause in 7 percent of crashes and near-crashes. For the study, drivers had onboard "black boxes" that recorded their actions.

Last year, 41,059 people died in traffic accidents.

Aegis' software will work on phones with Windows Mobile software, popular for "smart" phones, or Symbian software, used in phones from Nokia and Sony Ericsson. It uses the phone's Global Positioning System chip to detect motion, aided by the cell-tower signal. If the phone has a Wi-Fi antenna, that can be used as well, said Dave Hattey, Aegis' CEO.

To work, the software has to be supported by the cellular carrier. Aegis has no deals in place yet, but is in discussions with the big U.S. networks, said Teater, who is a vice president at Aegis. The company hopes to be able to announce early next year that the software is available through a carrier, probably for $10 to $20 per month for a family.

The software can be managed remotely through a Web site. For instance, parents will get alerts if their kids override the motion-sensing feature to indicate that they're riding in car rather than driving. A corporation that buys the software for their employees can do the same.

Unusually for the world of cell phone software, Aegis is bringing out DriveAssistT in partnership with an insurance company. Nationwide Mutual Insurance Co. said it plans to offer a discount of 3 percent to 10 percent on family policies for people who use DriveAssistT

Monday, 13 October 2008

Parkinson's linked to vitamin D

Scientists are testing whether vitamin D supplements can ease symptoms of Parkinson's disease.

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A US team found 55% of Parkinson's patients had insufficient levels of vitamin D, compared to 36% of healthy elderly people.

However, the Emory University researchers do not yet know if the vitamin deficiency is a cause or the result of having Parkinson's.

The study appears in the journal Archives of Neurology.

Parkinson's disease affects nerve cells in several parts of the brain, particularly those that use the chemical messenger dopamine to control movement.

The most common symptoms are tremor, stiffness and slowness of movement. These can be treated with oral replacement of dopamine.

Previous studies have shown that the part of the brain affected most by Parkinson's, the substantia nigra, has high levels of the vitamin D receptor, which suggests vitamin D may be important for normal functions of these cells.

Sunlight

Vitamin D is found in the diet, but is primarily formed in the skin by exposure to sunlight.

However, the body's ability to produce the vitamin decreases with age, making older people more prone to deficiency.

One theory is that people with Parkinson's may be particularly vulnerable because their condition limits the amount of time they spend out of doors.

However, scientists say it may also be possible that low vitamin D levels are in some way related to the genesis and origin of the disease.

The researchers examined vitamin D levels in 100 people with Parkinson's, 100 with Alzheimer's disease and 100 who were healthy. The groups were matched for age, and economic circumstance.

Among the Parkinson's group 23% of patients had vitamin D levels so low that they could be described as deficient. In the Alzheimer's group the figure was 16%, and in the healthy group 10%.

The researchers said the findings were striking because the study group came from the South West of the US, where sunny weather is the norm.

'Intriguing finding'

Researcher Dr Marian Evatt said: "We found that vitamin D insufficiency may have a unique association with Parkinson's, which is intriguing and warrants further investigation."

Dr Kieran Breen, director of research, Parkinson’s Disease Society said: "Further research is required to determine at what stage the deficiency in vitamin levels occur in the brains of people with Parkinson's and whether the provision of a dietary supplement, or increased exposure to sunlight may help alleviate symptoms or have an affect on the rate of the condition's progression.

"This would help us answer the question as to whether the decrease in vitamin D levels in Parkinson’s is a cause or effect of the condition."

Doctors have known for decades that vitamin D plays a role in bone formation.

More recently, scientists have been uncovering its effects elsewhere, including producing peptides that fight microbes in the skin, regulating blood pressure and insulin levels, and maintaining the nervous system.

Low vitamin D levels also appear to increase the risk of several cancers and auto-immune diseases such as multiple sclerosis and diabetes.

Asian stocks repeat US successes

Financial markets in Asia have risen sharply, with the Nikkei gaining 13% in morning trading, and Sydney up 5%.

Happier Wall Street traders
New York had good news at last

The gains came after Wall Street shares rocketed 11% on Monday as investors welcomed fresh moves to deal with the worldwide financial crisis.

Investors were helped by news the US government wanted to put in place its $700bn bank bail-out quickly.

Australian Prime Minister Kevin Rudd has now announced a A$10.4bn ($7.3bn) economic stimulus package.

It will allow for one-off payments to the country's low-wage earners and pensioners and follows earlier announcements of guarantees of bank deposits for three years.

According to Mr Rudd, the strategy "will strengthen the national economy and support Australian households".

Australian PM Kevin Rudd announces a A$10.4bn economic stimulus package

By lunchtime, Sydney's S&P/ASX200 was up 219 points at 4399.7, and the Australian dollar had strengthened against the US dollar, trading four cents higher than on Monday.

In New Zealand, the stock market rose 6.7% by early afternoon.

In the US, President George W Bush is due to make a statement shortly before markets open there later on Tuesday.

He will speak after meeting his working group on financial markets.

Rescue plans

On Monday US Treasury and Federal Reserve Bank officials met the chief executives of some of America's biggest banks, to work out details of the US government's $700bn (£400bn) bail-out package.

HAVE YOUR SAY
It seems Mr Brown and Co. have no choice in this matter and these takeovers are necessary, but its very wrong that it is the tax payer that should have to do this
Anthony Halpin, Aberdeen

The US has said it was also getting ready to follow in Europe's footsteps and purchase stakes in financial institutions.

On Monday the US Treasury announced it was set to buy stakes in a "broad array" of financial firms.

Treasury Secretary Henry Paulson will give further details of the plan on Tuesday morning, with an expectation that funds will be injected into such major banks as JP Morgan Chase, Goldman Sachs and the Bank of New York Mellon Corp.

European governments have said they are putting up to 1.7 trillion euros ($2.3 trillion; £1.3 trillion) to protect the continent's banks through guarantees and other emergency measures.

The sums are a maximum, and might not all be spent if the financial crisis eases.

So far Germany has approved a bank rescue plan worth up to 500bn euros, France will spend about 350bn euros, the Netherlands has pledged 200bn euros, Spain 100bn euros, and Austria 85bn euros.

Italy said it would spend as much as was needed, without giving any exact figures.

The bulk of the European money will be used to guarantee lending between banks - part of a plan agreed this weekend by the 15 nations that use the euro.

The cash will also be used to take stakes in ailing banks, with the UK government saying it would inject up to £36bn of taxpayers cash into Royal Bank of Scotland, Lloyds TSB and HBOS.

City hopes to shuttle people in futuristic 'podcars'

The thought of a driverless, computer-guided car transporting people where they want to go on demand is a futuristic notion to some.

Computer-guided electric podcars like these carry small groups of people on their own networks.

Computer-guided electric podcars like these carry small groups of people on their own networks.

To Jacob Roberts, podcars -- or PRTs, for personal rapid transit -- represent an important component in the here-and-now of transportation.

"It's time we design cities for the human, not for the automobile," said Roberts, president of Connect Ithaca, a group of planning and building professionals, activists and students committed to making this upstate New York college town the first podcar community in the United States.

"In the podcar ... it creates the perfect blend between the privacy and autonomy of the automobile with the public transportation aspect and, of course, it uses clean energy," Roberts said.

With the oil crisis reaching a zenith and federal lawmakers ready to begin fashioning a new national transportation bill for 2010, Roberts and his colleagues think the future is now for podcars -- electric, automated, lightweight vehicles that ride on their own network separate from other traffic.

Unlike mass transit, podcars carry two to 10 passengers, giving travelers the freedom and privacy of their own car while reducing the use of fossil fuels, reducing traffic congestion and freeing up space now monopolized by parking.

At stations located every block or every half-mile, depending on the need, a rider enters a destination on a computerized pad, and a car would take the person nonstop to the location. Stations would have slanted pull-in bays so that some cars could stop for passengers, while others could continue unimpeded on the main course.

"It works almost like an elevator, but horizontally," said Roberts, adding podcar travel would be safer than automobile travel.

The podcar is not entirely new. A limited version with larger cars carrying up to 15 passengers was built in 1975 in Morgantown, West Virginia, and still transports West Virginia University students.

Next year, Heathrow Airport outside London will unveil a pilot podcar system to ferry air travelers on the ground. Companies in Sweden, Poland and Korea are already operating full-scale test tracks to demonstrate the feasibility. Designers are planning a podcar network for Masdar City, outside Abu Dhabi, which is being built as the world's first zero-carbon, zero-waste city.

Meanwhile, more than a dozen cities in Sweden are planning podcar systems as part of the country's commitment to be fossil-fuel-free by 2020, said Hans Lindqvist, a councilman from Varmdo, Sweden, and chairman of Kompass, an association of groups and municipalities behind the Swedish initiative.

"Today's transportation system is reaching a dead end," said Lindqvist, a former member of the European parliament.

Cars have dominated the cityscape for nearly a century, taking up valuable space while polluting the air, said Magnus Hunhammar, chief executive officer of the Stockholm-based Institute for Sustainable Transportation, the world's leading center on podcar technology.

"Something has to change," he said. "We aren't talking about replacing the automobile entirely. We are adding something else into the transportation strategy."

Skeptics, however, question whether podcars can ever be more than a novelty mode of transportation, suitable only for limited-area operations, such as airports, colleges and corporate campuses. Detractors, mainly light-rail advocates, say a podcar system would be too complex and expensive.

"It is operationally and economically unfeasible," said Vukan Vuchic, a professor of transportation and engineering at the University of Pennsylvania who has written several books on urban transportation.

"In the city, if you have that much demand, you could build these guideways and afford the millions it would take, but you wouldn't have capacity. In the suburbs, you would have capacity, but the demand would be so thin you couldn't possibly pay for those guideways, elevated stations, control systems and everything else," Vuchic said.

Podcars typically run on an elevated guideway or rails, but they also can run at street level. As a starting point, pilot podcar networks can be built along existing infrastructure, supporters say.

Ithaca Mayor Carol Peterson said a podcar network could be part of her upstate city's long-range transportation plans and its mission of developing urban neighborhoods that are environmentally sustainable and pedestrian-friendly. Ithaca has a long history of progressive achievements -- this summer, it began the first community-wide car sharing program in upstate New York.

In Ithaca, a network could connect the downtown business district and main business boulevard with the campuses of Cornell University and Ithaca College, which sit on hillsides flanking the city. When the two colleges are in session, Ithaca's population balloons from about 30,000 to about 80,000, causing big-city congestion on the city's roads.

Santa Cruz, California, recently hired a contractor to design a small solar-powered podcar system that would loop through the city's downtown and along its beach front.

The Institute for Sustainable Transportation predicts a podcar system will be installed in an American city within the next five years, although it is likely to cost tens of millions of dollars. Because of the huge initial investment, funding would have to come from both public and private sectors, IST officials said.

The capital cost is about $25 million to $40 million per mile, which includes guideways, vehicles and stations, compared with $100 million to $300 million a mile for light-rail or subway systems, according to the IST.

Although the plan for Ithaca is only in the conceptual stages, Roberts sees the city as a logical place for the country's first community-wide podcar network, noting that construction of the Erie Canal across upstate New York in the early 1800s revolutionized commercial transportation in a young America.

"Buffalo, Rochester, Syracuse, Albany are connected along a single line, the Erie Canal. Now, they are connected by the (New York State) Thruway. It would be easy to adapt. You could have a high-speed rail line, or even buses, deliver travelers to the podcar stations, and the podcars take them wherever they want to go in the city," he said.

But podcar developers say they have overcome most technological obstacles and now must overcome the political and cultural barriers that lie ahead, equating it to the mind-set revolution that occurred when Americans hitched up their horses for good to become a nation of motorists.

"We are introducing an alternative to the automobile for the first time in 100 years," said Christopher Perkins, chief executive officer of Unimodal Transport Solutions, a California company that builds podcars that operate on magnetic levitation instead of wheels.


Thursday, 9 October 2008

The Hubble Space Telescope gleams after a servicing mission in 2002.


NASA
The Hubble Space Telescope gleams after a servicing mission in 2002.

The Hubble Space Telescope's handlers are weighing a plan to turn on a never-used backup system to restore communications as early as next week. If it works, the world's favorite orbiting observatory could be back in business just a couple of days later. If it doesn't, Hubble could conceivably be worse off than it was before.

The space telescope has been out of commission since Sept. 27, when its command and data-handling system abruptly failed. That forced a postponement of NASA's final Hubble servicing mission, which was due to begin this week with the launch of the shuttle Atlantis. The launch has been put off until next year - to give mission planners time to figure out how to make a fix, and to give Atlantis' crew time to practice the operation.

In the meantime, engineers have a devised a plan to switch Hubble's data-handling functions from the primary system, known as Side A, to the Side B backup system. Side B hasn't been put to the test since Hubble went into orbit in 1990.

"The transition to Side B operations is complex," Hubble's managers explained in a mission update released after the breakdown. "It requires that five other modules used in managing data also be switched to their B-side systems."

All the reconfigurations would be made remotely, by beaming commands to Hubble from the ground.

Sources familiar with the plans for the switchover note that there's some risk that the Side B systems won't work. There's even a chance that if the A-to-B switch doesn't work, Hubble wouldn't be able to switch back from B to A. That scenario would complicate plans for the eventual repair mission, and thus provides an argument for leaving things alone until Atlantis arrives.

A spare data-handling unit is being tested at NASA's Goddard Space Flight Center in Maryland, where the Hubble operations team is based. Engineers are also analyzing diagnostic data, according to NASASpaceflight.com, an independent Web site that closely follows the space program.

Hubble's managers reviewed the plans for the A-to-B switch today during a round of meetings at Goddard. More meetings are planned on Friday, and NASA Headquarters would review the recommendations on Tuesday, after the federal Columbus Day holiday.

If NASA's top officials give the go-ahead, the switchover could take place as early as Wednesday. Science operations could resume a couple of days after the switch has been made.

"If Side B goes up, and it's successful, we're looking forward to resuming science observations and coming up with clever programs to fill the time," said Ray Villard, a spokesman for the Baltimore-based Space Telescope Science Institute.

He said the first of Hubble's instruments to be brought back up would be the Wide Field and Planetary Camera 2, or WFPC2. He said reviving Hubble's other working camera, the Near Infrared Camera and Multi-Object Spectrometer, or NICMOS, would be "trickier" because of the camera system's cryogenics. Hubble's Fine Guidance Sensors could conceivably be used for science as well.

Hubble's other two science instruments, the Advanced Camera for Surveys and the Space Telescope Imaging Spectrograph, are currently out of commission and have been slated for repair during Atlantis' visit. Two more instruments, the Wide Field Camera 3 and the Cosmic Origins Spectrograph, are ready for installation.

NASA was already planning to have Atlantis' astronauts do all those upgrades, and change out Hubble's worn-out batteries and gyroscopes as well. Now more complications lie ahead. Will Hubble's handlers go through with the temporary switchover? How will they adjust the spacewalk schedule and the cargo manifest to accommodate the definitive fix for the data-handling system? Stay tuned for next week's episode of "Hubble's Troubles."

Testicles Could Be New Source Of Stem Cells

Scientists from Germany and the UK have found a new source of stem cells that could be as good as embryonic stem cells for researching and developing treatments for a range of serious diseases, but without the ethical problems of embryonic stem cells; the source is routine biopsies of men's testicles.
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The discovery was the work of researchers from the Universities of Tübingen and Cologne in Germany, and King's College, London, and was published on 8th October in the online issue of Nature. The lead author was Professor Thomas Skutella, who leads an experimental embryology group at Tübingen University.

Stem cells from embryos have the potential to become any cell in the body, after all, a whole person grows from a single fertilized egg. But getting stem cells from embryos is fraught with ethical problems since it involves the destruction of embryos.

For some time now scientists have been working to find alternative ways to make stem cells with the same ability to become any cell in the body as the embryonic stem cell. One such method that has been showing great promise recently is the induced pluripotent stem cell, or iPS cell. By taking a normal cell, such as a skin cell and inserting certain genes into its DNA, scientists have been able to reprogram the cell to regress to an earlier form when it still had the potential to become virtually any other cell of the body.

However, Skutella and colleagues had a hunch that there was another source of stem cells, ones that did not need to have genes inserted into their DNA to make them into cells that produce other cells, because they do that already: the sperm producing cells inside adult male testicles.

They succeeded in harvesting stable stem cells from spermatogonial (sperm producing) cells taken from routine tissue biopsies of the testes of 22 adult male humans. They showed that the cells could be coaxed into regressing to become cells from all three germ layers that form in the very early stages of a new human embryo. This was done by culturing them in the same way used to make embryonic stem cells differentiate.

The researchers concluded that:

"The generation of human adult germline stem cells from testicular biopsies may provide simple and non-controversial access to individual cell-based therapy without the ethical and immunological problems associated with human embryonic stem cells."

Stem cells are the new hope for treatment development because they carry the potential of personalized therapy - using a person's own cells to create stem cells that can then repair and replace damaged tissue, such as in Parkinson's, Alzheimer's and cancers. This way the big problem of immune system rejection is overcome because the implants have the same DNA as the host.

In this case however, using stem cells from male testes, the treatment would only work on men.

Many scientists are of the view that regardless of the alternatives that are found, embryonic stem cells are still the best, they are the "gold standard" of pluripotency, and we will need them for research and treatment development for some time to come.

Obama: McCain's mortgage plan shows 'erratic' leadership

Sen. Barack Obama is saying Sen. John McCain has "shifting positions" and shows "erratic" leadership.Sen. Barack Obama on Thursday slammed Sen. John McCain's new mortgage plan as "the latest in a series of shifting positions" and evidence of "erratic and uncertain leadership."
Sen. Barack Obama is saying Sen. John McCain has "shifting positions" and shows "erratic" leadership.

Sen. Barack Obama is saying Sen. John McCain has "shifting positions" and shows "erratic" leadership.
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"He's ended up with a plan that punishes taxpayers, rewards banks, and won't solve our housing crisis," Obama said at an event in Dayton, Ohio.

At the second presidential debate Tuesday, McCain suggested that the government buy up bad home loan mortgages and renegotiate at the new diminished value of those homes.

Under McCain's proposed $300 billion mortgage rescue plan, much of the burden of paying to keep troubled borrowers in their homes would shift to taxpayers.

McCain's original plan called for lenders to write down the value of these mortgages and take those losses.

Doug Holtz-Eakin, McCain's economic adviser, said Wednesday that the McCain plan could be put into place quickly because the groundwork and the authority for it already have been provided by last week's $700 billion bailout bill; the Hope for Homeowners program authorized by the housing rescue bill passed in July; and the government takeover of mortgage giants Fannie Mae and Freddie Mac. Read the details of McCain's proposal

In an e-mail to supporters, McCain said his plan would address "the very root of the failing housing market."

Obama charged that McCain's latest plan is "risky."

"I don't think we can afford that kind of erratic and uncertain leadership in these uncertain times. We need steady leadership in the White House. We need a president we can trust in times of crisis," Obama said.

n response to Obama's remarks in Dayton, the McCain campaign said Obama was "putting politics above the national interest."

"John McCain's home ownership resurgence plan represents absolutely no new expense to the taxpayer, but simply refocuses priorities to more directly assist the homeowners who are hurting instead of greed on Wall Street," spokesman Tucker Bounds said in a statement.

Earlier Wednesday, Obama's campaign launched a television ad that takes aim at McCain's proposal, saying "the same lenders that caused the crisis in the first place" would benefit from the plan.

As the candidates enter the final weeks of campaigning, they have been attacking each other more aggressively.

McCain's campaign has launched a string of new ads that question Obama's judgment and character.

The McCain campaign calls Obama "too risky for America" in a new Web ad that focuses on his political relationship with Bill Ayers, a founding member of the radical Weather Underground.

"Barack Obama and domestic terrorist Bill Ayers. Friends. They've worked together for years. But Obama tries to hide it," the announcer says in the 90-second ad.

"But Obama's friendship with terrorist Ayers isn't the issue. The issue is Barack Obama's judgment and candor," the announcer says. Video Watch analysts weigh in on the McCain attacks »

At a town hall meeting in Waukesha, Wisconsin, angry voters pleaded with McCain to get tougher on Obama.

One voter suggested that McCain bring up the Rev. Jeremiah Wright controversy.

"I am begging you, sir, take it to him," the voter said.

McCain did not specifically address the comment about Wright, Obama's former pastor who came under scrutiny during the primaries after clips of his sermons circulated on the Internet.

On Ayers, the Arizona senator said he doesn't care about a "washed-up former terrorist," but vowed to press Obama on his candor and judgment.

"We need to know the full extent of the relationship because of whether Sen. Obama is telling the truth to the American people or not. That's the question," McCain said.

Weather Underground was involved in bombings in the early 1970s, including attacks on the Pentagon and the Capitol. Obama was a young child at the time of the bombings.

Obama and Ayers, now a university professor, met in 1995, when both worked with a nonprofit group trying to raise funds for a school improvement project and a charitable foundation. CNN's review of project records found nothing to suggest anything inappropriate in the volunteer projects in which the two men were involved. Fact check: How close are Obama and Ayers?

Quoted in The New York Times, Obama called Ayers "somebody who engaged in detestable acts 40 years ago, when I was 8."

Michelle Obama brushed off the latest round of attacks in an interview with CNN's Larry King on Wednesday.

"I don't know anyone in Chicago who's heavily involved in education policy who doesn't know Bill Ayers. But, again, I go back to the point that the American people aren't asking these questions," she said. Video Watch Michelle Obama's interview »

Obama said her husband has been "thoroughly vetted" and said the Ayers allegations are a "part of politics."

The McCain campaign started pushing hard on the Ayers connection this past weekend when Alaska Gov. Sarah Palin accused Obama of "palling around with terrorists who would target their own country."

The Obama campaign retaliated Monday with a 13-minute documentary Web video detailing the Arizona senator's involvement in the Keating Five scandal in the 1980s.